Zachary Seguin

CHEM Courses

CHEM 1 – Pre-University Chemistry

Essential preparation for first year chemistry courses. Formulae, nomenclature, stoichiometry, an introduction to thermochemistry, solution chemistry, chemical equilibria, acids, bases, oxidation-reduction reactions, kinetics and bonding.

CHEM 100 – Introduction to Chemical Sciences

The Chemist in society: Lectures, workshops, or seminars focusing on academic and professional development [Offered: F]

CHEM 101 – Introduction to Biochemical Sciences

The Biochemist in society: Lectures, workshops, or seminars focusing on academic and professional development [Offered: F]

CHEM 120 – Physical and Chemical Properties of Matter

The stoichiometry of compounds and chemical reactions. Properties of gases. Periodicity and chemical bonding. Energy changes in chemical systems. Electronic structure of atoms and molecules; correlation with the chemical reactivity of common elements, inorganic and organic compounds.

CHEM 120L – Chemical Reaction Laboratory 1

Selected experiments for students taking CHEM 120. [Offered: F]

CHEM 123 – Chemical Reactions, Equilibria and Kinetics

Properties of liquids and solutions. Introduction to chemical equilibria. Principles of acid-base equilibria, solubility and electrochemical processes. Chemical kinetics.

CHEM 123L – Chemical Reaction Laboratory 2

Selected experiments for students taking CHEM 123.

CHEM 140 – Introduction to Scientific Calculations

The application of numeric computing software to perform basic calculations, data analysis, regression analysis, plotting of scientific graphs, data manipulation, and equation solving will be covered in this course, with an emphasis placed upon chemical and biochemical concepts and applications. [Offered: F,W,S]

CHEM 140L – Introductory Scientific Calculations Laboratory

An introductory laboratory for the use and applications of computer software packages, such as Excel and Mathcad, for scientific calculations. The use of such software packages for basic calculations, data analysis, regression analysis, plotting of scientific graphs, data manipulation, and equation solving will be covered, with an emphasis placed upon chemical and biochemical concepts and applications. [Offered: F,W]

CHEM 200 – Introduction to Laboratory Techniques

This course is an introduction to practical laboratory skills. Laboratory techniques will include: the separation, isolation and purification of compounds (through extraction, reflux, distillation, chromatography, and recrystallization), analysis techniques, and the application of these techniques in synthesis. The subjects covered in this biweekly laboratory provide the foundation for more advanced laboratory courses and the basic training needed for an industrial or research laboratory position. The seminar portion of this course will focus on communication and technical skills; the latter will include analysis of Material Safety Data Sheets (MSDS), use of search engines, and learning of citation formats. [Offered: F]

CHEM 201 – Environmental Impact and Management of Resources 1

Introduction to the management of resources used in the production, conversion and disposal/recycling of chemicals. Biobased versus fossil resources. Introduction to the life cycle analysis of a material. Principles of green chemistry. [Offered: F; Based in Bordeaux; online only]

CHEM 209 – Introductory Spectroscopy and Structure

The nature of electromagnetic radiation and an elementary outline of quantum mechanics in one dimension. For each of microwave, infrared, Raman, electronic, photoelectron, and nuclear magnetic resonance spectroscopy, the nature of the molecular energy levels involved and the type of molecular information that can be obtained using it are examined. [Offered: F]

CHEM 212 – Structure and Bonding

An introduction to the principles of chemical structure and bonding, with emphasis on their application to inorganic systems. Topics include: atoms, orbitals, and periodicity; localized bonding models; symmetry and group theory; and molecular orbital theory. The subjects treated in this course are foundational components for advanced studies in all areas of chemistry. [Offered: W,S]

CHEM 212W – Physical Chemistry (WLU)

CHEM 217 – Chemical Bonding

Atomic and molecular structure. Molecular symmetry. Localized bonding models. Molecular orbital theory. Structures of solids. [Not open to students in the following plans: Biochemistry, Chemical Physics, Chemistry, Computational Science (Biochemistry Specialization), Computational Science (Chemistry Specialization), Geochemistry, Science and Business (Biochemistry Specialization), Science and Business (Chemistry Specialization). Offered: F]

CHEM 220 – Intro Analytical Chemistry

Quantitative and analytical chemistry including ionic equilibria, classical and more recent methods. Emphasis on planning and decision-making in the analytical process. [Offered: F]

CHEM 220L – Analytical Chemistry Lab 1

Selected experiments for students taking CHEM 220 or 228. [Offered: F]

CHEM 221 – Multi-Component Analysis

Instrumental analytical chemistry, including traditional and more recent methods. Emphasis on planning and decision-making in the analytical process. [Offered W,S]

CHEM 224L – Analytical Chemistry Laboratory 2

Extensive lab experience for students who have taken CHEM 220. [Offered: W,S]

CHEM 228 – Chemical Analysis

An introduction to methods of quantitative chemical analysis. [Not open to students in the following plans: Biochemistry, Chemical Physics, Chemistry, Geochemistry, Science and Business (Biochemistry Specialization), Science and Business (Chemistry Specialization), Offered: W]

CHEM 228L – Analytical Chemistry Laboratory for Life Sciences

Selected experiments for students taking CHEM 228. [Offered: S]

CHEM 233 – Fundamentals of Biochemistry

Chemistry of amino acids, carbohydrates, lipids and nucleic acids, with special emphasis on representative proteins and enzymes, including hemoglobin, cytochrome c and chymotrypsin. [Offered: W,S]

CHEM 233L – Fundamentals of Biochemistry Laboratory

Selected experiments for students taking CHEM 233 or CHEM 239. [Offered: W, S]

CHEM 237 – Introductory Biochemistry

An introduction to the chemistry of amino acids, carbohydrates, lipids and nucleic acids. Structure and properties of proteins and enzymes. [Offered: W, S]

CHEM 237L – Introductory Biochemistry Laboratory

Selected experiments for students taking CHEM 237. [Offered: W, S]

CHEM 239 – Introduction to Biological Systems

Introduction to the biology and biochemistry of a selection of plants and microorganisms, with emphasis on the chemical components of living matter (nucleic acids, amino acids, carbohydrates, lipids, DNA, RNA, peptides, proteins) and the synthesis and breakdown of complex molecules in plants and microorganisms. [Offered: W; online only]

CHEM 240 – Mathematical Methods for Chemistry

Mathematical techniques useful for chemistry students. Introduction to complex numbers, plus topics chosen from: calculus; differential equations; vector spaces and vector algebra; matrices and determinants; elementary probability theory; basic group theory and symmetry. Applications to problems of chemical interest. [Offered: F]

CHEM 250L – Physical Chemistry Laboratory 1

Selected experiments for students in year two. [Offered: F]

CHEM 254 – Introductory Chemical Thermodynamics

An introduction to the first, second and third laws of thermodynamics and the application of these laws to ideal systems, mixtures, and chemical reactions. Thermodynamic principles are used to study changes in state, including phase changes, and to establish the link between the equilibrium constant and the properties of the substances involved in a chemical reaction. [Offered: W,S]

CHEM 262 – Organic Chemistry for Engineering

Bonding, structure and nomenclature in organic chemistry. Physical properties and simple reactions associated with the important functional groups.[Offered: F,W]

CHEM 262L – Organic Chemistry Laboratory for Engineering Students

Selected experiments for engineering students taking CHEM 262.[Offered: F,W]

CHEM 264 – Organic Chemistry 1

Structure and bonding in organic chemistry. Isomerism and stereoisomerism in organic compounds. Acidity of organic compounds and substituent effects on acidity. Reaction mechanisms and energetics. Chemistry of alkanes, haloalkanes, alcohols and ethers, alkenes and alkynes. [Offered: F, S]

CHEM 265 – Organic Chemistry 2

Nucleophilic addition and substitution at CO carbon. Aromaticity and simple MO theory of conjugated systems. Electrophilic and nucleophilic aromatic substitution reactions. Applications of spectroscopic techniques in organic chemistry. [Offered: W,S]

CHEM 265L – Organic Chemistry Laboratory 1

Selected experiments for students taking CHEM 265. [Offered: W,S]

CHEM 266 – Basic Organic Chemistry 1

Structure, nomenclature and reactions of important classes of organic compounds. Stereochemistry and its role in reaction mechanisms. [Offered: F]

CHEM 266L – Organic Chemistry Laboratory

Selected experiments for students taking (or who have taken) CHEM 266.

CHEM 267 – Basic Organic Chemistry 2

A continuation of the concepts of CHEM 266, including material on amines, aromatics, enols and enolates, and nucleophilic addition and substitution at the carbonyl group. Introduction to nuclear magnetic resonance and infrared spectroscopy. [Offered: W]

CHEM 267L – Organic Chemistry Laboratory

Selected experiments for students taking CHEM 267.

CHEM 301 – Environmental Impact and Management of Resources 2

Indices and methods for quantifying the environmental impact of chemical and biochemical processes. Life cycle analysis of processes, starting from the extraction of the required raw materials through to the disposal or recycling of the products. Introduction to regulatory policies. [Offered: W; Based in Bordeaux; online only]

CHEM 302 – Innovation and Project Management

Examples drawn from the chemical industry are used to expose students to a methodology for developing an innovative idea into a well-defined working plan. Students will use the methodology to develop ideas for their fourth-year projects. [Offered: F; online only]

CHEM 305 – Atmospheric Chemistry and Physics

The chemistry and physics of the terrestrial atmosphere, with emphasis on the operation of major anthropogenic influences, such as ozone depletion, the greenhouse effect and tropospheric systems, such as photochemical smog. Other planetary atmospheres will be discussed in the context of their implications for the evolution of the earth's atmosphere. [Offered: W]

CHEM 305L – Atmospheric Modelling Laboratory

This course provides an introduction to modern regional air quality modelling. The models used are Models-3, the U.S. Environmental Protection Agency's tropospheric modelling framework and MM-5, the meteorology model developed by the U.S. National Center for Atmospheric Research. The course covers the major elements in regional air quality modelling: emissions databases, chemical modelling, and the role of meteorology. A team-oriented modelling project relevant to Southern Ontario air quality will be carried out. [Offered: W]

CHEM 310 – Transition Element Compounds and Inorganic Materials

The inorganic, organic and solid state chemistry of the d-block elements. The structure and physical properties of coordination compounds and transition metal containing solids. The role of transition metal organometallics in catalysis. [Offered: F]

CHEM 310L – Inorganic Chemistry Laboratory 2

Synthesis of transition and non-transition metal compounds. Characterization of compounds using IR, UV-VIS and NMR spectroscopy. [Offered: F]

CHEM 313 – Main Group and Solid State Chemistry

This course provides a detailed examination of the structure and bonding in main group and solid state compounds, including valence bond and molecular orbital theory for describing electronic structures, Hueckel and extended Hueckel approximations. Structures of simple solids, including close packing of spheres and derived ionic lattice types; aspects of chemical crystallography, Bravais lattices, point groups, space groups, crystal planes, and X-ray diffraction; Ionic interactions in gases and solution; the thermodynamics of acid-base interactions; descriptive chemistry and characterization of main group element compounds. [Offered: W]

CHEM 313L – Inorganic Chemistry Laboratory 1

Introduction to synthetic inorganic chemistry. [Offered: W]

CHEM 323 – Analytical Instrumentation

Detailed study of selected instruments and instrumental methods. Introduction to chemometrics and to computer interfacing. [Offered: F]

CHEM 331 – Fundamentals of Metabolism 1

Thermodynamics of metabolism. Metabolism of carbohydrates and lipids. Chemistry of oxidative phosphorylation and photosynthesis. Emphasis is put on the role and chemical mechanisms of the enzymes in these processes [Offered: F]

CHEM 333 – Metabolism 1

Metabolism of carbohydrates, lipids and amino acids. [Offered: F]

CHEM 335L – Advanced Biochemistry Laboratory

Selected experiments for students having completed or concurrently taking CHEM 331. Topics to be covered include: NMR, allostery, enzymology, electrophoresis, carbohydrates, lipids, photosynthesis, and respiration. [Offered: F,W]

CHEM 339 – Methods and Tools for Biosyntheses

Biochemical reactions involved in respiration, fermentation, cell metabolism. Enzymatic reactions and their use in major industrial processes for transforming or producing chemicals. Biodigesters and bioreactors. Critical analysis of various processes using energy and mass balances. [Offered: F; online only]

CHEM 340 – Introductory Computational Chemistry

Introduction to the theory and practice of computational methods used in chemistry. Use of molecular modeling software to investigate the electronic structure and geometry of molecules, to calculate potential energy surfaces for chemical reactions, and to predict and understand the behaviour of chemical systems. [Offered: W]

CHEM 340L – Introductory Computational Chemistry Laboratory

Introduction to the theory and practice of computational methods used in chemistry. Use of molecular modeling software to investigate the electronic structure and geometry of molecules, to calculate potential energy surfaces for chemical reactions, and to predict and understand the behaviour of chemical systems. [Offered: F, W]

CHEM 350 – Chemical Kinetics

Basic chemical kinetics; treatment of kinetic data; complex reaction mechanisms; fast reactions; the canonical ensemble and the canonical partition function; statistical mechanics applied to chemistry; statistical theory of reaction rates. [Offered: W]

CHEM 350L – Physical Chemistry Laboratory 2

Selected experiments for students in year three. [Offered: F]

CHEM 356 – Introductory Quantum Mechanics

Historical background; the differential equation approach to quantum mechanics; treatments of solvable problems such as the particle-in-a-box, harmonic oscillator, rigid rotator and the hydrogen atom; introduction to approximation methods for more complicated systems.

CHEM 357 – Physical Biochemistry

The use of diffusion, ultracentrifugation, osmotic pressure, eletrophoresis and X-ray diffraction to study the properties of biopolymers. Hyperbolic and allosteric enzyme kinetics, inhibition and regulation. Some spectroscopies important to the life sciences. [Offered: W]

CHEM 360 – Organic Chemistry 3

Enolate alkylation, condensation, conjugate addition and pericyclic reactions. FMO theory, organometallics and transition metal-catalyzed C-C bond formation. [Offered: W]

CHEM 360L – Senior Organic Chemistry Laboratory

Selected microscale synthetic experiments for students in Year Three Chemistry and Biochemistry programs, including spectroscopic identification of organic compounds. [Offered: W]

CHEM 363 – Organic Process Chemistry

This course is an introduction to the important aspects of Process Chemistry for the industrial production of pharmaceutically active organic compounds. Topics covered include: industrial organic synthesis and process design, scaling to kilogram quantities, green chemistry principles, process safety and hazard identification, industrial separation and purification, and meeting quality guidelines and regulations. [Offered: F or W]

CHEM 370 – Introduction to Polymer Science

Basic definitions and polymer nomenclature, molecular weight averages and distributions, constitutional and configurational isomerism, rubber elasticity, step-growth and free radical chain growth polymerizations, emulsion polymerization. [Offered: F]

CHEM 381 – Bioorganic Chemistry

Review of stereochemistry, racemic and enantioselective syntheses of amino acids, peptide synthesis, development of peptides into drugs, physical properties and structures of monosaccharides, reactions of monosaccharides, glycoside synthesis, structures of disaccharides and polysaccharides, synthesis of oligosaccharides, physical properties and synthesis of nucleosides, nucleotides, and nucleic acids, nucleotides and nucleic acids as drugs, general drug development. [Offered: W]

CHEM 382L – Advanced Organic Synthesis Laboratory

A laboratory course intended for students in the Medicinal Chemistry Specialization of the Honours Chemistry plan. The purpose of this course is to introduce students to advanced laboratory techniques used in synthetic organic chemistry. [Offered: F]

CHEM 383 – Medicinal Chemistry

This course discusses the drug discovery process and drug synthesis. Topics include enzymes and receptors, hit and lead discovery, lead optimization, QSAR, prodrugs, drug delivery, drug metabolism, mechanisms of selected drugs and laboratory and process scale synthesis of selected drugs. [Formerly CHEM 482; Offered F]

CHEM 392A – Research Project 1

This course is only for exchange students wishing to carry out a research project.

CHEM 392B – Research Project 2

This course is only for exchange students wishing to carry out a research project.

CHEM 400 – Special Topics in Chemistry

A selection of current and advanced topics of interests in many areas of Chemistry. For a list of offerings see the Academic Advisor or check the Chemistry website, program electives page. [Formerly CHEM 410, 420, 440, 450, 460 and 470; Offered: F, W]

CHEM 404 – Physicochemical Aspects of Natural Waters

Properties of water; chemicals in the environment; environmental fate of inorganic and organic pollutants; basic phenomena affecting the fate of water pollutants (vapor pressure; activity, solubility, partitioning, diffusion, sorption); acids and bases in water; dissolved carbon dioxide; trace metals in water. [Offered: F or W]

CHEM 406 – Environmental Organic Chemistry

Anthropogenic organic compounds in the environment; how and why they get there. Phase transport through the ecosystem. Biological and non-biological chemical transformations. Prevention and remediation. [Offered: W]

CHEM 410 – Special Topics in Inorganic Chemistry

For a current list of offerings see the Undergraduate Officer.

CHEM 420 – Special Topics in Analytical Chem

For a current list of offerings see the Undergraduate Officer. [Formerly CHEM 425. Offered: F,W.]

CHEM 430 – Special Topics in Biochemistry

For a current list of offerings see the Undergraduate Officer.

CHEM 432 – Metabolism 2

Properties and metabolism of porphyrins, purines, pyrimidines and biogenic amines. Biosynthesis and mode of action of selected cofactors. Structure-function relationships of enzymes. Regulation of enzyme activity. [Offered: F]

CHEM 433 – Advanced Biochemistry

Nitrogen fixation. Assimilation of nitrogen. Amino acid metabolism. Metabolic regulation. Proteolytic enzymes, ubiquitin. Blood coagulation. Signal transduction and amplification. Biochemistry of nitric oxide. Biochemistry of vision. [Offered: W]

CHEM 440 – Special Topics in Computational/Theoretical Chemistry

For a current list of offerings see the Undergraduate Advisor. [Offered: F,W]

CHEM 450 – Special Topics in Physical Chemistry

For a current list of offerings see the Undergraduate Officer. [Formerly CHEM 452. Offered: F,W ]

CHEM 460 – Special Topics in Organic Chemistry

For a current list of offerings see the Undergraduate Officer.

CHEM 464 – Spectroscopy in Organic Chemistry

Elucidation and identification of organic structures by contemporary spectroscopic techniques. [Offered: F]

CHEM 470 – Special Topics in Polymer Chemistry

For a current list of offerings see the Undergraduate Advisor. [Offered: F,W]

CHEM 479 – Preparation of Biobased Compounds and Materials

Catalysis and biocatalysis. "Green solvent" and solvent-free reactions. Biobased synthesis of polymers and amphiphiles. Bioreactions in chemical synthesis. [Offered: F; online only]

CHEM 481 – Rational Design of Potential Drug Candidates

This course provides an introduction to strategies for design of potential drug candidates. It builds upon molecular modelling principles introduced in CHEM 340 and will apply them to specific problems in drug design. Topics include: conformational analysis, molecular mechanics, and molecular dynamics; computational studies of drug-receptor interactions, docking of small organic molecules to biological receptors, and alteration of molecular structures for improvement of bioactivity.

CHEM 482 – Advanced Topics in Medicinal Chemistry

This course discusses the drug discovery process and drug synthesis. Topics include enzymes and receptors, hit and lead discovery, lead optimization, QSAR, prodrugs, drug delivery, drug metabolism, mechanisms of selected drugs and laboratory and process scale synthesis of selected drugs.

CHEM 491A – Biobased Chemistry Research Project 1

Student teams work on the projects defined in CHEM 302 (Innovation and Project Management). [Offered: F]

CHEM 491B – Biobased Chemistry Research Project 2

Students work individually on extending the scope of the team projects started in CHEM 491A. [Offered: W]

CHEM 494A – Research Project

Laboratory work on a senior year research project. Enrolment into this course requires permission of the CHEM 494 co-ordinator. See the CHEM 494 coordinator for course details. No credit or grade will be provided for this course until the two-term sequence CHEM 494A/B has been completed. CHEM 494A/B may not be taken concurrently without prior permission of the CHEM 494 co-ordinator.

CHEM 494B – Research Project

A continuation of CHEM 494A. No credit or grade will be provided for this course until the two-term sequence CHEM 494A/B has been completed. CHEM 494A/B may not be taken concurrently without prior permission of the CHEM 494 co-ordinator.

CHEM 495 – Advanced Research Project

This course is only for exchange students wishing to carry out an advanced research project during the fall term.

CHEM 496 – Advanced Research Project

This course is only for exchange students wishing to carry out a research project during the winter term.

CHEM 497 – Advanced Research Project

This course is only for exchange students wishing to carry out a research project during the spring term.

CHEM 710 – Selected Topics in Inorganic Chemistry

Discussion of specialized topics related to the research interests of members of the Centre. Special topics could include, for example, bioinorganic chemistry; inorganic reaction mechanisms; synthetic methods in inorganic and organometallic chemistry; homogeneous and heterogeneous catalysis; chemistry of polynuclear compounds.

CHEM 712 – X-Ray Crystallography

Introduction: crystals, basic concepts; space groups; the reciprocal lattice; x-ray diffraction; the phase problem; structure factors; electron density; small molecule structure solution, structure refinement, structure results, journals and data bases, paper writing.

CHEM 713 – Chemistry of Inorganic Solid State Materials

Introduction to solid state chemistry, common crystal structures, principles of solid state synthesis, theory and experimental methods for characterizing solids, including thermal analysis techniques, powder x-ray and neutron diffraction methods; special topics to include one or more of the optical, electronic, magnetic, or conductive properties of inorganic materials.

CHEM 715 – Structure & Bonding in Inorganic Chemistry

Free electron, Hueckel and extended Hueckel methods for molecules and clusters. Perturbation theory. Applications of group theory in inorganic chemistry; Jahn-Teller effects in molecular and solids. Energy bands in one, two and three dimensions.

CHEM 717 – Advanced Transition Metal Chemistry

Magnetochemistry of transition metal compounds. Electronic spectra of complex ions including applications of molecular orbital and ligand field theories. Stabilization of unusual oxidation states and coordination numbers. Bonding, structure and reactivity of certain important classes of metal complexes, e.g. metal hydrides, metal-metal bonded species, biologically-significant model systems such as macrocycles.

CHEM 718 – Advanced Organometallic Chemistry

Reactions, structure and bonding of organometallic compounds of transition and non-transition metals.

CHEM 720 – Selected Topics in Analytical Chemistry

Special topics could include for example: trace analysis using modern instrumental and spectroscopic methods; advanced mass spectrometry (instrumentation and interpretation of spectra); analytical aspects of gas and liquid chromatography.

CHEM 724 – Chemical Instrumentation

Instrumental components and optimum application; rudiments of design; electrical, spectral, migrational and other methods.

CHEM 726 – Topics in Analytical Spectroscopy

Atomic emission and absorption spectroscopy; methods of excitation and detection; quantitative applications. Molecular electronic spectroscopy: UV, visible and Raman; instrumental characteristics; applications to quantitative determinations, speciation, measurements of equilibrium, etc. Sources and control of errors and interferences. Determination and description of colour.

CHEM 727 – Separations

Material to be covered will be drawn from the following topics: Diffusion; Isolation of organic material from the matrix; Chromatographic techniques - principles of chromatographic separations; Gas (GLC, GSC), Liquid (LLC, LSC, GPC, IEC), Supercritical Fluid (SFC) Chromatographies; GC-MS, GC-FTIR; Electrophoresis; Flow field fractionation.

CHEM 728 – Electroanalytical Chemistry

A study of electroanalytical techniques and their role in modern analytical chemistry. The underlying principles will be developed. Techniques will include chronoamperometry, chronocoulometry, polarography, voltammetry, chronopotentiometry, coulometric titrations, flow techniques, electrochemical sensors and chemically modified electrodes.

CHEM 729 – Surface Analysis

Modern surface analysis: description and importance of surfaces. Surface area determinations. High surface area solids, supports. Scanning electron microscopy: principles and applications. Auger electron spectroscopy. Applications in metallurgy and materials science. Depth profiling. ESCA: elemental compositions and studies of catalyst surfaces. SIMS. Infrared spectroscopy. Studies of supported metal and metal oxides. Acid surface sites and their role in catalysis. Scanning tunnelling microscopy; theory and applications. Single crystal surfaces. LEED. Studies of chemisorption.

CHEM 730 – Proteins and Nucleic Acids

Protein structure and function; intermolecular interactions and protein-protein association. Nucleic acid and DNA structure; protein-nucleic acid interactions.

CHEM 731 – Selected Topics in Biochemistry

Discussion of specialized topics related to the research interests of the members of the Centre. For example, recent offerings have included: Metalloproteins and Metalloenzymes; Heme Proteins; Chemistry of Enzymatic Reaction Mechanisms; Peptides - Synthesis, Structure and Function; Food Enzymology; Advanced Microbial Physicology; NMR in Biological Systems.

CHEM 736 – Regulations in Biological Systems

Regulation of replication, transcription, translation, RNA processing, and protein degradation. Cell cycle and control of cell division.

CHEM 737 – Enzymes

Discussion of the underlying factors contributing to enzyme, abzyme and ribozyme catalysis.

CHEM 738 – Cell Membranes and Cell Surfaces

Structure, function and dynamics of membrane lipids and proteins. Membrane transport. Biogenesis and trafficking of membrane proteins. Signal transduction.

CHEM 740 – Selected Topics in Theoretical Chemistry

Discussion of specialized topics related to the research interests of the members of the Centre. Special topics could include for example: theory of intermolecular forces; density matrices; configuration interaction; correlation energies of open and closed shell systems; kinetic theory and gas transport properties; theory of the chemical bond.

CHEM 745 – Statistical Mechanics

Review of classical and quantum mechanics; principles of statistical mechanics; applications to systems of interacting molecules; imperfect gases, liquids, solids, surfaces and solutions.

CHEM 746 – Quantum Chemistry

Approximate solutions of the Schrodinger equation and calculations of atomic and molecular properties.

CHEM 750 – Selected Topics in Physical Chemistry

Discussion of specialized topics related to the research interests of members of the Centre. Special topics could include for example: principles of magnetic resonance in biological systems; collisions, spectroscopy and intermolecular forces, surface chemistry; catalysis; electrolyte theory; non-electrolyte solution theory; thermodynamics of biological systems; thermodynamics.

CHEM 755 – Kinetics - Dynamics

Empirical analysis. Kinetic theory of gases. Potential energy surfaces. Unimolecular rates. Relaxation and steady state methods. Diffusion rates. Rates between polar molecules. Energy transfer.

CHEM 756 – Spectroscopy

Aspects of electronic vibrational and rotational spectroscopy of atoms, molecules, and the solid state. Relevant aspects of quantum mechanics, Dirac notation, and angular momentum will be discussed. Group Theory will be presented and its implications for spectroscopy introduced.

CHEM 760 – Selected Topics in Organic Chemistry

Two or three topics from a range including: bio-organic chemistry; environmental organic chemistry; free radicals; heterocyclic molecules; molecular rearrangements; organometallic chemistry; photochemistry; natural products.

CHEM 764 – Synthetic Organic Reactions

Named organic reactions and other synthetically useful reactions will be discussed. The mechanism, stereochemical implications and use in organic synthesis of these rections will be presented. Examples from the organic literature will be used to illustrate these aspects.

CHEM 765 – Strategies in Organic Synthesis

The synthesis of organic compounds is discussed and emphasis is placed on the design of synthetic routes. Examples drawn from the literature are used to illustrate this synthetic planning.

CHEM 766 – Organic Spectroscopy

Ultraviolet, infrared, resonance spectroscopy and mass spectrometry, with emphasis on applications to studies of organic molecules.

CHEM 769 – Physical Organic Chemistry

Linear free energy relationships; substituent effects and reactive intermediates.

CHEM 770 – Principles of Polymer Science

Introduction to the physical chemistry of high polymers, principles of polymer synthesis, mechanisms and kinetics of polymerization reactions, copolymerization theory, polymerization in homogeneous and heterogeneous systems, chemical reactions of polymers. Theory and experimental methods for the molecular characterization of polymers.

CHEM 771 – Physical Properties of Polymers

The physical properties of polymers are considered in depth from a molecular viewpoint. Rubber elasticity, mechanical properties, rheology and solution behaviour are quantitatively treated.

CHEM 772 – Polymerization and Polymer Reactions

The reactions leading to the production of polymers are considered with emphasis on emulsion and suspension polymerization and polymerization reaction engineering. Polymer degradation, stabilization and modification are also considered in depth.

CHEM 773 – Selected Topics in Polymer Chemistry

Discussion of specialized topics of polymer chemistry related to the research interests of the faculty or prominent scientific visitors. Special topics could include, for example, polymer stabilization and degradation; mechanical properties; polymer principles in surface coatings; organic chemistry of synthetic high polymers; estimation of polymer properties; reactions of polymers; polymerization kinetics.

CHEM 794 – Master's Seminar

A written research proposal, and a public seminar and defence of this proposal, to be given by all MSc students within two terms of entering this program.