Zachary Seguin

BME Courses

BME 101 – Communications in Biomedical Engineering-Written and Oral

This course introduces first-year students to biomedical engineering with a focus on the engineering profession and technical communication skills. Through in-class and independent activities leading to formative and summative assessments, students will consider and reflect on communication intention, audience, content, medium, format, and tone to demonstrate and improve upon their listening, written and oral communication skills for academic, engineering, and professional context. [Offered: F]

BME 101L – Communications in Biomedical Engineering-Visualization

This laboratory course introduces students to visual communication methods relevant to engineering analysis and design. Through in-class and independent activities leading to formative and summative assessments, students will consider and reflect on communication intention, audience, content, medium, format, and level of detail to demonstrate and improve upon their skills in graphing, freehand sketching, technical drawing, and computer-aided design (CAD). [Offered: F]

BME 102 – Seminar

Biomedical Engineering first-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: W]

BME 121 – Digital Computation

The key skills necessary to develop software solutions to solve biomedical engineering problems. Topics include software development, software design, programming language syntax, object oriented programming, structured programming, arrays, matrices, pointers, and algorithm efficiency. The topics will be reinforced in the context of practical biomedical software systems such as physiological monitoring systems and clinical support systems. [Offered: F]

BME 122 – Data Structures and Algorithms

Topics of structured software design, data structures, abstract data types, recursive algorithms, algorithm and data structure analysis and design from both computational and memory perspectives, lists, stacks, queues, trees, graphs, sorting and searching, hashing, and problem-solving strategies. Embedded programming in health monitoring systems and healthcare management systems. [Offered: W]

BME 161 – Introduction to Biomedical Design

Topics related to biomedical design will be covered: multidisciplinary system design, design process, problem definition, life-cycle design, design specification, function analysis, design evaluation and decision-making, introduction to mechanical design, prototyping, experimentation, safety and responsibility in engineering design, design for society and environment, and design documentation. [Offered: F]

BME 162 – Human Factors in the Design of Biomedical and Health Systems

Design of human-machine environments, designing for patient safety and reduce human error in decision making, analytical methods of determining user needs, information processing and human sensory processes and consideration of these elements in the design of systems with humans, and consideration of human physical capabilities in ergonomic design. Topics will be reinforced in the context of the design of prosthetics or rehabilitation devices. [Offered: W]

BME 181 – Physics I - Statics

Introduction to the basic theory and principles of mechanics of static systems. Topics covered include: statics of particles, rigid bodies and force systems, equilibrium of rigid bodies, analysis of joints and frames, distributed forces, centroids and moments of inertia, and friction. Applications of mechanical principles to musculoskeletal systems will be presented. [Offered: F]

BME 182 – Physics II - Dynamics

The science of motion is taught with initial focus on particles, and then progressing to planar rigid body systems. Concepts such as inertia, momentum, work, energy, Newton's laws, and contact dynamics are covered, with particular application to human motions (e.g., walking, running, jumping, lifting, and throwing). [Offered: F]

BME 184 – Engineering Biology

Introduction to basic concepts of biochemistry and cell biology. Overview of the chemistry of amino acids, carbohydrates, lipids and nucleic acid. Structure and properties of proteins and enzymes. Elements of cell structure and diversity, and relationship of biochemistry with cell metabolism. A focus on biomedical engineering with relevant examples such as biomimetic engineering design, system biology and tissue engineering. [Offered: W]

BME 184L – Engineering Biology Laboratory

Laboratory experiments for students taking BME 184. [Offered: W]

BME 186 – Chemistry Principles

The stoichiometry of compounds and chemical reactions. Periodicity and chemical bonding. Energy changes in chemical systems. Electronic structure of atoms and molecules, correlation with the chemical reactivity of common elements, inorganic and organic compounds. Discussion of the structure, nomenclature and reactions of important classes of organic compounds. Stereochemistry and its role in reaction mechanisms. [Offered: W]

BME 201 – Seminar

Biomedical Engineering second-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: F]

BME 202 – Seminar

Biomedical Engineering second-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: S]

BME 213 – Statistics and Experimental Design

Fundamentals of probability and statistics, and applications to biomedical engineering. Random variables and statistical distributions, statistical estimation, hypothesis testing, regression, and experiment design considerations. Applications to biomedical experiments, biomedical imaging data, and clinical trials. [Offered: F]

BME 252 – Linear Signals and Systems

Models and analysis of linear systems in the context of measurement and processing of biosignals such as electroencephalography (EEG), electrocardiography (ECG), and electromyography. Discrete and continuous time systems, difference and differential equations, impulse and frequency response, transform domain techniques, transfer functions and frequency response, frequency domain analysis of linear systems, sampling theory, stability, and linear filters. [Offered: S]

BME 261 – Prototyping, Simulation and Design

Problem solving approaches, agile design and development, rapid prototyping, revision control, design patterns, development cycles, and simulation. Topics will be reinforced in the context of biomedical engineering projects conducted in groups within a collaborative environment. [Offered: F]

BME 281 – Mechanics of Deformable Solids

Introduction to mechanical response of materials and stress-strain relationship. Behaviour of prismatic members in tension, compression, shear, bending and torsion. Shear-force and bending-moment diagrams. Introduction to instability. Mechanical properties of biological tissues, and viscoeleastic models. Applications to bone, cartilage, and biomedical implants. [Offered: F]

BME 281L – Mechanics of Deformable Solids Laboratory

Laboratory experiments for students taking BME 281. [Offered: F]

BME 282 – Materials Science for Biomedical Engineers

Crystalline structure, crystal defects, non-crystalline materials, structure and properties of metals, ceramics, glasses, semi-conductors, polymers, and composites. Factors in materials design, material selection and processing in the context of biomedical devices and instruments will also be discussed.[Offered: S]

BME 283 – Chemistry Principles

The stoichiometry of compounds and chemical reactions. Periodicity and chemical bonding. Energy changes in chemical systems. Electronic structure of atoms and molecules, correlation with the chemical reactivity of common elements, inorganic and organic compounds. Discussion of the structure, nomenclature and reactions of important classes of organic compounds. Stereochemistry and its role in reaction mechanisms. [Offered: F, first offered Fall 2015]

BME 284 – Physiological and Biological Systems

The structure, functions and properties of the major biological systems (musculoskeletal, nervous, cardiovascular) will be presented in relation to the design of biomedical devices (imaging, assistive, and diagnostic). Concepts in modeling biological systems will be introduced. Various aspects of pathology and how they influence medical device design will also be discussed. [Offered: S]

BME 284L – Physiology and Anatomy Laboratory

Laboratory experiments for students taking BME 284. [Offered: S]

BME 285 – Engineering Biology

Introduction to basic concepts of biochemistry and cell biology. Overview of the chemistry of amino acids, carbohydrates, lipids and nucleic acid. Structure and properties of proteins and enzymes. Elements of cell structure and diversity, and relationship of biochemistry with cell metabolism. A focus on biomedical engineering with relevant examples such as biomimetic engineering design, system biology and tissue engineering. [Offered: F]

BME 285L – Engineering Biology Laboratory

Laboratory experiments for students taking BME 285. [Offered: F]

BME 286 – The Physics of Medical Imaging

The fundamental laws of electricity, magnetism and optics will be taught through the introduction to basic concepts of medical imaging: radiation for imaging, x-ray, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound or sonography imaging, electric impedance tomography, confocal microscopy, fluoroscopy. Radionuclide imaging: Single Photon Emission Computed Tomography (SPECT), and Positron Emission Computed Tomography (PET). Emerging technologies: Elastography, THz imaging, Molecular imaging will also be discussed. [Offered: S, first offered Spring 2016]

BME 292 – Digital Systems

Digital technology, combinatorial logic, binary arithmetic, sequential circuits, digital design, and microcontrollers. Topics will be reinforced in the context of biomedical microcontrollers and sensors used in physiological monitoring and clinical support systems. [Offered: S]

BME 292L – Digital Systems Laboratory

Laboratory experiments for students taking BME 292, focusing on circuit construction, simulation, and design. [Offered: S]

BME 294 – Circuits, Instrumentation, and Measurements

Basic concepts of hardware measurement systems pertaining to the measurement of biosignals: active and passive circuit elements, Kirchhoff's laws, mesh and nodal circuit analysis, principle of superposition, step responses of first and second order networks, sinusoidal steady state analysis, input-output relationships, transfer functions and frequency response of linear systems, operational amplifiers, analog signal detection, conditioning and conversion systems, transducers, difference and instrumentation amplifiers, A/D and D/A conversion. Examples will be presented in the form of physiological monitoring hardware for vital measurements such as electroencephalography (EEG), electrocardiography (ECG), and electromyography (EMG). [Offered: S]

BME 294L – Circuits, Instrumentation, and Measurements Laboratory

Laboratory experiments for students taking BME 294. [Offered: S]

BME 301 – Seminar

Biomedical Engineering third-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: W]

BME 302 – Seminar

Biomedical Engineering third-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: F]

BME 351 – Linear Signals and Systems

Models and analysis of linear systems in the context of measurement and processing of biosignals such as electroencephalography (EEG), electrocardiography (ECG), and electromyography. Discrete and continuous time systems, difference and differential equations, impulse and frequency response, transform domain techniques, transfer functions and frequency response, frequency domain analysis of linear systems, sampling theory, stability, and linear filters. [Offered: W, first offered Winter 2017]

BME 352 – Control Systems

Classical and state space representations of control systems. Stability, controllability, observability and sensitivity. Routh-Hurwitz and root-locus methods. Frequency domain behaviour, Bode plots, Nyquist stability criteria. Pole placement, PID, phase-lead and phase-lag controllers. Application to anatomical system models, including musculoskeletal and cardiovascular systems, and to physiological feedback systems. [Offered: F, first offered Fall 2017]

BME 352L – Control Systems Laboratory

Laboratory experiments for students taking BME 352. [Offered: F, first offered Fall 2017]

BME 353 – Control Systems

Classical and state space representations of control systems. Stability, controllability, observability and sensitivity. Routh-Hurwitz and root-locus methods. Frequency domain behaviour, Bode plots, Nyquist stability criteria. Pole placement, PID, phase-lead and phase-lag controllers. Application to anatomical system models, including musculoskeletal and cardiovascular systems, and to physiological feedback systems. [Offered: W, first offered Winter 2017]

BME 353L – Control Systems Laboratory

Laboratory experiments for students taking BME 353. [Offered: W, first offered Winter 2017]

BME 354 – Anatomical Systems Modeling

Introduction to systems theory as a general modeling method, and applied to the skeletal, neuromuscular, central nervous, cardiovascular, and respiratory systems of the human body. Time-domain simulations, sensitivity analyses, and parameter identification, with the latter driven by experimental measurements of system performance. [Offered: F, first offered Fall 2017]

BME 355 – Anatomical Systems Modelling

Introduction to systems theory as a general modeling method, and applied to the skeletal, neuromuscular, central nervous, cardiovascular, and respiratory systems of the human body. Time-domain simulations, sensitivity analyses, and parameter identification, with the latter driven by experimental measurements of system performance. [Offered: W]

BME 356 – Control Systems

Classical and state space representations of control systems. Stability, controllability, observability and sensitivity. Routh-Hurwitz and root-locus methods. Frequency domain behaviour, Bode plots, Nyquist stability criteria. Pole placement, PID, phase-lead and phase-lag controllers. Application to anatomical system models, including musculoskeletal and cardiovascular systems, and to physiological feedback systems. [Offered: F]

BME 356L – Control Systems Laboratory

Laboratory experiments for students taking BME 356. [Offered: F]

BME 361 – Biomedical Engineering Design

Design methods: problem definition, requirements analysis, criteria and generation of alternative solutions, feasibility analysis, and optimization. Product development. Design survey of biomedical equipment and assistive technologies. A term-long design project in small groups. [Offered: W]

BME 362 – Biomedical Engineering Design Workshop 1

Engineering design project course where students work in small groups applying the principles of engineering problem solving, systems analysis, simulation, optimization and design to a biomedical engineering problem of their own choosing. Lecture topics include project management, risk management, standards, regulatory clearance and certification for biomedical devices. [Offered: F]

BME 364 – Engineering Biomedical Economics

This course examines key economic issues in health care and biomedical industries. Topics include the market for medical care, health insurance, various models of healthcare delivery and competition and the role of government in policy, financing and delivery of health care. This course will train students to use economic analysis to model and understand the complex interactions between health care delivery, insurance markets, health innovators, governments, and firms. [Offered: F]

BME 381 – Biomedical Engineering Ethics

This course explores ethical issues in biomedical engineering practice, including professional ethics, medical ethics, the ethics of human and animal subject use in biomedical research, and the impact of biomedical engineering solutions on society and the environment. [Offered: W]

BME 384 – Biomedical Transport: Biofluids and Mass Transfer

Fundamental concepts in systems involving fluid flow. Basic treatment of statics, kinematics and dynamics of fluids. Mass transfer, conservation of mass, momentum and energy for a control volume. Dimensional analysis and similarity. Discussion of flow in pipes and channels and brief introduction to boundary layers, lift and drag, ideal and compressible flow will be specifically covered in the context of the cardiovascular system (macrocirculation and microcirculation). [Offered: F]

BME 386 – The Physics of Medical Imaging

The fundamental laws of electricity, magnetism and optics will be taught through the introduction to basic concepts of medical imaging: radiation for imaging, x-ray, computed tomography (CT), magnetic resonance imaging (MRI), ultrasound or sonography imaging, electric impedance tomography, confocal microscopy, fluoroscopy. Radionuclide imaging: Single Photon Emission Computed Tomography (SPECT), and Positron Emission Computed Tomography (PET). Emerging technologies: Elastography, THz imaging, Molecular imaging will also be discussed. [Offered: F]

BME 391 – Circuits, Instrumentation, and Measurements

Basic concepts of hardware measurement systems pertaining to the measurement of biosignals: active and passive circuit elements, Kirchhoff's laws, mesh and nodal circuit analysis, principle of superposition, step responses of first and second order networks, sinusoidal steady state analysis, input-output relationships, transfer functions and frequency response of linear systems, operational amplifiers, analog signal detection, conditioning and conversion systems, transducers, difference and instrumentation amplifiers, A/D and D/A conversion. Examples will be presented in the form of physiological monitoring hardware for vital measurements such as electroencephalography (EEG), electrocardiography (ECG), and electromyography (EMG). [Offered: W, first offered Winter 2017]

BME 391L – Circuits, Instrumentation, and Measurements Laboratory

Laboratory experiments for students taking BME 391. [Offered: W, first offered Winter 2017]

BME 392 – Circuits, Instrumentation, and Measurements

Basic concepts of hardware measurement systems pertaining to the measurement of biosignals: active and passive circuit elements, Kirchhoff's laws, mesh and nodal circuit analysis, principle of superposition, step responses of first and second order networks, sinusoidal steady state analysis, input-output relationships, transfer functions and frequency response of linear systems, operational amplifiers, analog signal detection, conditioning and conversion systems, transducers, difference and instrumentation amplifiers, A/D and D/A conversion. Examples will be presented in the form of physiological monitoring hardware for vital measurements such as electroencephalography (EEG), electrocardiography (ECG), and electromyography (EMG). [Offered: F]

BME 392L – Circuits, Instrumentation, and Measurements Laboratory

Laboratory experiments for students taking BME 392. [Offered: F]

BME 393 – Digital Systems

Digital technology, combinatorial logic, binary arithmetic, sequential circuits, digital design, and microcontrollers. Topics will be reinforced in the context of biomedical microcontrollers and sensors used in physiological monitoring and clinical support systems. [Offered: W]

BME 393L – Digital Systems Laboratory

Laboratory experiments for students taking BME 393, focusing on circuit construction, simulation, and design. [Offered: W]

BME 399 – Directed Biomedical Research Project

A biomedical research project carried out under the supervision of a faculty member. Students interested in graduate studies or industrial research careers will gain experience in advanced research techniques and develop valuable research skills. A written report is to be submitted to the course co-ordinator. This course is extra over and above the normal course load. Good standing and permission of department is required for registration.

BME 401 – Seminar

Biomedical Engineering fourth-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: F]

BME 402 – Seminar

Biomedical Engineering fourth-year students will meet with a faculty member designated as their class professor. Performance in assignments, conceptual difficulties with courses, interrelation of coursework, later work and engineering practice will be discussed. Non-credit course. [Offered: W]

BME 411 – Optimization and Numerical Methods

Interpolation and curve fitting, root-finding methods, local and global optimization methods, constrained optimization, multiobjective and multidisciplinary design optimization for biomedical applications such as implanted chips and therapeutic regimens. [Offered: F]

BME 450 – Sports Engineering

This course focuses on the application of engineering principles to the analysis of sports equipment and their effects on athletic performance. Principles of mechanics are used to understand the motion and forces arising in sports equipment, and their interaction with the musculoskeletal dynamics of athletes. [Offered: F]

BME 451 – Biomechanics of Human Movement

This course introduces students to the biomechanics of the musculoskeletal system, including motor control and rehabilitation engineering. Multibody models in two-dimensional (2D) and three-dimensional (3D) will be used to study the dynamics of normal and pathological motions. Motor control will be included, as well as the identification of body segment parameters and the dynamics of muscles. Applications may include assistive devices, rehabilitation, human gait, occupational biomechanics and other activities. [Offered: W]

BME 461 – Biomedical Engineering Design Workshop 2

The first half of a two-term engineering design project continuing the biomedical design workshop sequence. A prototype and interim progress report are presented at the end of the first term. Lecture topics include safety and risk analysis of biomedical technologies. [Offered: F]

BME 462 – Biomedical Engineering Design Workshop 3

The concluding half of the fourth year Biomedical Engineering Design Workshop. [Offered: W, first offered Winter 2019]

BME 487 – Special Topics in Biomedical Signals

This course deals with selected topics at the undergraduate level in medical imaging and diagnostics, biosignals and neuroscience. (Note: each year at least one elective course will be offered in this theme area. For a current list of offerings, see the Director for Biomedical Engineering.) [Offered: F, W]

BME 488 – Special Topics in Biomechanics

This course deals with selected topics at the undergraduate level in biofluid mechanics, tissue mechanics, sports engineering and rehabilitation engineering. (Note: each year at least one elective course will be offered in this theme area. For a current list of offerings, see the Director for Biomedical Engineering.) [Offered: F, W]

BME 489 – Special Topics in Biomedical Devices

This course deals with selected topics at the undergraduate level in assistive devices, implants, prostheses, orthoses, biomedical technologies, therapeutics and biocompatibility. (Note: each year at least one elective course will be offered in this theme area. For a current list of offerings, see the Director for Biomedical Engineering.) [Offered: F, W]

BME 499 – Elective Biomedical Research Project

A major undergraduate individual biomedical research project carried out as a technical elective (TE) under the supervision of a faculty member. Students are expected to demonstrate initiative and responsibility. An oral presentation of results and a written report are the minimum requirements. The faculty supervisor or department may set other requirements. Students will arrange for a faculty supervisor prior to registration. [Offered: F,W]